Congratulations Zaighum Abbas for the PDB prize on the VI Latin American Crystallographic Association School and Meetin (VI LACA)!
Congratulations Zaighum Abbas for the PDB prize on the VI Latin American Crystallographic Association School and Meetin (VI LACA)!
Our newest septin paper is out!
The X-ray structure of the hetero-coiled coil reveals interesting molecular details regarding septin-septin recognition and the features that facilitate their interaction with partners.https://t.co/pfVfaDE9eEWith the Crump Group and @WoolfsonLab
— Italo Cavini (@CaviniItalo) October 18, 2023
https://twitter.com/septinpapers/status/1669251279787556864?s=20
Well done Luis, for receiving the best poster prize at the 52nd Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology (SBBq)!
Congratulations Deborah!
(from Instagram, May 19th 2023)
AlphaFold came to change the game! Here, aided by an AF model, we have dissected the binding interface of Borg’s BD3 motif to the heterodimeric septin coiled coil SEPT6-SEPT7. It interacts with the furrow formed by the helices of the parallel CC. Upon binding in vitro, it leads to an exacerbated septin polymerization. The manuscript also contains polymerization studies on CTD-truncated septin subunits.
Access the publication here:
https://www.sciencedirect.com/science/article/abs/pii/S0022283623002048
Congrats to Adriano, the newest PhD from our group!
https://twitter.com/CaviniItalo/status/1608506522660900864
Congrats Eloy on the dissertation about the study of a SEPT9 chimera!
Another great defense in our group! Danielle got just her PhD, presenting data uncovering new details on the interaction of septins with BD3 from Borg3. Such an exciting topic!